中文名稱(chēng)： 兔抗MDC1(Phospho-Ser513) 多克隆抗體
英文名稱(chēng)： Anti-MDC1(Phospho-Ser513) rabbit polyclonal antibody
別 名： NFBD1
相關(guān)類(lèi)別： 一抗
儲(chǔ) 存： 冷凍（-20℃） 避光
宿 主： Rabbit
抗 原： MDC1(Phospho-Ser513)
反應(yīng)種屬： Human
標(biāo) 記 物： Unconjugate
克隆類(lèi)型： Unconjugate
技術(shù)規(guī)格
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Background: |
The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. [provided by RefSeq, Jul 2008] |
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Applications: |
IHC |
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Name of antibody: |
MDC1(Phospho-Ser513) |
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Immunogen: |
Peptide sequence around phosphorylation site of Serine 513(E-R-S(p)-Q-A) derived from Human MDC1. |
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Full name: |
mediator of DNA-damage checkpoint 1 |
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Synonyms： |
NFBD1 |
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SwissProt: |
Q14676 |
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IHC positive control: |
Human brain tissue |
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IHC Recommend dilution: |
50-100 |
